%0 Journal Article %T X-Ray Structure of Human Sulfide:Quinone Oxidoreductase: Insights into the Mechanism of Mitochondrial Hydrogen Sulfide Oxidation %J - %D 2019 %R https://doi.org/10.1016/j.str.2019.03.002 %X £¿ A hydrophilic H 2S-oxidizing site is connected to a hydrophobic tunnel that binds CoQ £¿ Cys201 is optimally positioned to form a postulated 4a-thiolate flavin intermediate £¿ A unique electropositive depression serves as a binding site for sulfane acceptors £¿ This hollow may also funnel negatively charged substrates to the H 2S-oxidizing sit %U https://www.cell.com/structure/fulltext/S0969-2126(19)30080-2