%0 Journal Article
%T Absence of Cytosolic 2-Cys Prx Subtypes I and II Exacerbates TNF-¦Á-Induced Apoptosis via Different Routes
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2019.01.081
%X £¿ Absence of Prx I and Prx II exacerbates TNF-¦Á-induced apoptosis in cancer cells. £¿ Prx I binds histone H2AX and inhibits DNA damage-dependent apoptosis. £¿ Prx II binds and prevents the oxidative activation of cIAP1 E3 ligase. £¿ Absence of Prx II induces cell-autonomous apoptosis and inhibits tumor growth
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30110-X