%0 Journal Article %T Defining Macrophages in the Heart One Cell at a Time %J - %D 2019 %R https://doi.org/10.1016/j.it.2019.01.010 %X Macrophages in the heart have dual roles in injury and repair after myocardial infarction, and understanding the two sides of this coin using traditional ¡®bulk cell¡¯ technologies has been challenging. By combining genetic fate-mapping and single-cell transcriptomics, a new study ( Nat. Immunol. 2019;20:29¨C39) reveals how distinct macrophage populations expand and diverge across the healthy heart and after infarction %U https://www.cell.com/trends/immunology/fulltext/S1471-4906(19)30021-3