%0 Journal Article
%T Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange
%J -
%D 2019
%R https://doi.org/10.1016/j.celrep.2019.03.035
%X £¿ SWR1C catalyzes two cycles of H2A.Z deposition by a biphasic, asymmetric reaction £¿ Binding of SWR1C enhances nucleosome dynamics £¿ Initial eviction of an H2A-H2B dimer involves ATP-dependent histone-DNA unwrapping £¿ Nucleosomal DNA sequence can modulate the rate of H2A.Z exchang
%U https://www.cell.com/cell-reports/fulltext/S2211-1247(19)30351-1