%0 Journal Article %T A high-resolution X chromosome copy-number variation map in fertile females and women with primary ovarian insufficiency %J - %D 2019 %R https://doi.org/10.1038/s41436-019-0505-2 %X Sex-biased expression of genes on the X chromosome is accomplished by a complex mechanism of dosage regulation that leads to anatomical and physiological differences between males and females. Copy-number variations (CNVs) may impact the human genome by either affecting gene dosage or disturbing a chromosome structural and/or functional integrity %U https://www.nature.com/articles/s41436-019-0505-2