%0 Journal Article
%T 1-Amino-2¡ä-fucosyllactose inhibits biofilm formation by Streptococcus agalactiae
%J -
%D 2019
%R https://doi.org/10.1038/s41429-019-0151-6
%X 2¡ä-Fucosyllactose (2¡ä-FL) is a ubiquitous oligosaccharide in human milk. Importantly, this carbohydrate promotes the growth of several strains of Bifidobacteria, a class of beneficial gut commensal, and inhibits epithelial binding of pathogens. In light of these protective effects, we elected to evaluate the potential of 2¡ä-FL to serve as an antibacterial agent against Group B Streptococcus (GBS). While 2¡ä-FL was devoid of any substantial antimicrobial or antibiofilm activity, conversion of 2¡ä-FL to its reducing end ¦Â-amine provided a novel antibiofilm compound
%U https://www.nature.com/articles/s41429-019-0151-6