%0 Journal Article %T Evidence- and consensus-based recommendations for the use of pegvaliase in adults with phenylketonuria %J - %D 2018 %R https://doi.org/10.1038/s41436-018-0403-z %X Phenylketonuria (PKU) is a rare metabolic disorder that requires life-long management to reduce phenylalanine (Phe) concentrations within the recommended range. The availability of pegvaliase (PALYNZIQ£¿, an enzyme that can metabolize Phe) as a new therapy necessitates the provision of guidance for its use %U https://www.nature.com/articles/s41436-018-0403-z