%0 Journal Article
%T Integrated transcriptomic¨Cgenomic tool Texomer profiles cancer tissues
%J -
%D 2019
%R https://doi.org/10.1038/s41592-019-0388-9
%X Profiling of both the genome and the transcriptome promises a comprehensive, functional readout of a tissue sample, yet analytical approaches are required to translate the increased data dimensionality, heterogeneity and complexity into patient benefits. We developed a statistical approach called Texomer (https://github.com/KChen-lab/Texomer) that performs allele-specific, tumor-deconvoluted transcriptome¨Cexome integration of autologous bulk whole-exome and transcriptome sequencing data. Texomer results in substantially improved accuracy in sample categorization and functional variant prioritization
%U https://www.nature.com/articles/s41592-019-0388-9