%0 Journal Article %T Assessment of proportional hazard assumption in aggregate data: a systematic review on statistical methodology in clinical trials using time-to-event endpoint %J - %D 2018 %R https://doi.org/10.1038/s41416-018-0302-8 %X The evaluation of the proportional hazards (PH) assumption in survival analysis is an important issue when Hazard Ratio (HR) is chosen as summary measure. The aim is to assess the appropriateness of statistical methods based on the PH assumption in oncological trials %U https://www.nature.com/articles/s41416-018-0302-8