%0 Journal Article %T Nucleosome structure and dynamics are coming of age %J - %D 2018 %R https://doi.org/10.1038/s41594-018-0166-x %X Since the first high-resolution structure of the nucleosome was reported in 1997, the available information on chromatin structure has increased very rapidly. Here, we review insights derived from cutting-edge biophysical and structural approaches applied to the study of nucleosome dynamics and nucleosome-binding factors, with a focus on the experimental advances driving the research. In addition, we highlight emerging challenges in nucleosome structural biology %U https://www.nature.com/articles/s41594-018-0166-x