%0 Journal Article %T Forskolin attenuates the NLRP3 inflammasome activation and IL-1¦Â secretion in human macrophages %J - %D 2019 %R https://doi.org/10.1038/s41390-019-0418-4 %X The treatment of nucleotide-binding domain and leucine-rich repeat containing family, pyrin domain containing 3 (NLRP3) inflammasome-mediated pediatric inflammatory diseases is challenging. Here we studied whether cyclic adenosine monophosphate (cAMP) elevator forskolin could attenuate the nigericin-induced NLRP3-inflammasome activation and interleukin-1¦Â (IL-1¦Â) secretion in human macrophages %U https://www.nature.com/articles/s41390-019-0418-4