%0 Journal Article %T D-Serine Induced by Ocular Hypertension is Associated with Retinal Cell Death %A Hiroaki Sakaue %A Kei Tobiume %A Takashi Kanamoto %A Yasuhiro Ikeda %A Yasushi Kitaoka %A Yoshiaki Kiuchi %A Yusuke Murakami %J - %D 2018 %R 10.18314/ctoy.v1i1.1161 %X D-serine and serine racemase are localized to neurons in the adult mouse and human forebrain Balu DT, Takagi S, Puhl MD, Benneyworth MA, Coyle JT. Cell Mol Neurobiol.2014;34(3):419-435. CrossRef D-Serine as a glial modulator of nerve cells Miller RF. Glia.2004;47(3):275-283. CrossRef Direct calcium binding results in activation of brain serine racemase Cook SP, Galve-Roperh I, Mart¨ªnez del Pozo A, Rodr¨ªguez-Crespo I. J Biol Chem.2002;277(31):27782-27792. CrossRef Phosphorylation of mouse serine racemase regulates D-serine synthesis Foltyn VN, Zehl M, Dikopoltsev E, Jensen ON, Wolosker H. FEBS Lett.2010;584(13):2937-2941. CrossRef Cofactors of serine racemase that physiologically stimulate the synthesis of the N-methyl-D-aspartate (NMDA) receptor coagonist D-serine De Miranda J, Panizzutti R, Foltyn VN, Wolosker H. Proc Natl Acad Sci USA.2002;99(22):14542-14547. CrossRef Serine racemase: activation by glutamate neurotransmission via glutamate receptor interacting protein and mediation of neuronal migration Kim PM, Aizawa H, Kim PS, et al. Proc Natl Acad Sci USA.2005;102(6):2105-2110. CrossRef Serine racemase and the serine shuttle between neurons and astrocytes Wolosker H. Biochim Biophys Acta.2011;1814(11):1558-1566. CrossRef Light-evoked NMDA receptor-mediated currents are reduced by blocking d-serine synthesis in the salamander retina Stevens ER, Gustafson EC, Sullivan SJ, Esguerra M, Miller RF. Neuroreport.2010;21(4):239-244. CrossRef AMPA receptor mediated D-serine release from retinal glial cells Sullivan SJ, Miller RF. J Neurochem.2010;115(6):1681-1689. CrossRef Dynamic regulation of D-serine release in the vertebrate retina Gustafson EG, Stevens ES, Miller RF. J Physiol (Lond).2015;593(4):843-856. CrossRef A genetic variant of the serine racemase gene is associated with schizophrenia Morita Y, Ujike H, Tanaka Y, et al. Biol Psychiatry.2007;61(10):1200-1203. CrossRef Reduced D-serine to total serine ratio in the cerebrospinal fluid of drug naive schizophrenic patients Hashimoto K, Engberg G, Shimizu E, Nordin C, Lindstr£¿m LH, Iyo M. Prog Neuropsychopharmacol Biol Psychiatry.2005;29(5):767-769. CrossRef Multiple risk pathways for schizophrenia converge in serine racemase knockout mice, a mouse model of NMDA receptor hypofunction Balu DT, Li Y, Puhl MD, et al. Proc Natl Acad Sci USA.2013;110(26):E2400-2409. CrossRef Feedback inactivation of D-serine synthesis by NMDA receptor-elicited translocation of serine racemase to the membrane Balan L, Foltyn VN, Zehl M, et al. Proc Natl Acad Sci USA.2009;106(18):7589-7594. CrossRef Glaucoma neuroprotection: %U https://www.gratisoa.org/journals/index.php/CTOY/article/view/1161