%0 Journal Article
%T Multiple Myeloma and Primary Sjogren¡¯s Syndrome Combined with Unexplained Elevation of CA-125 Levels
%A Gang An
%A Jun Du
%A LuGui Qiu
%A ShuHui Deng
%J -
%D 2019
%R https://doi.org/10.18314/gjct.v5i1.1465
%X Background: Multiple myeloma (MM) and its precursor, monoclonal gammopathy of undetermined significance (MGUS), have been linked with several autoimmune conditions like primary Sj£¿gren¡¯s Syndrome (pSS). Several studies link MM with autoimmune disorders. However, the data has not yet been fully analyzed or systematized. Case presentation: We described a 60-year-old Chinese woman diagnosed as multiple myeloma who presented with ocular and oral sicca symptoms, unexplained elevation of CA-125. In this patient, there was an inner connection between MM and pSS remaining to be investigated further. Conclusions: Multiple myeloma and primary Sj£¿gren¡¯s Syndrome could be coexisting due to the similar physiopathologic mechanism, which might be the explanation of bortezomib¡¯s effectiveness. Moreover, tumor marker like CA-125 might be elevated owing to the secretion of CD-138+ve plasma cells
%U https://www.gratisoa.org/journals/index.php/GJCT/article/view/1465