%0 Journal Article %T Association between interleukin-4 (IL-4), gene polymorphisms (C-589T, T+2979G, and C-33T) and migraine susceptibility in Iranian population: A case¨Ccontrol study %A Mehdi Jahantigh %A Mohammad Reza Javan %A Nasrin Ranjbar %A Nima Sanadgol %A Nourollah Ramroodi %A Tooba Nakhzari Khodakheir %J - %D 2017 %X Background: Migraine is a chronic neurological disease characterized by recurrent moderate to severe headaches commonly in association with neuro-inflammation. Interleukin-4 (IL-4), an anti-inflammatory cytokine, plays an important role in modulating pain threshold and has an essential role in stimulation of pain receptors in the trigeminal nerve fibers. %K The current study aimed to investigate the possible associations between IL-4 single nucleotide polymorphisms (SNPs) and susceptibility to migraine in Iranian patients. %U https://www.ajol.info/index.php/ejhg/article/view/152191