%0 Journal Article
%T Role of Anti-mullerian Hormone (AMH), As A Prediction of Clinical Pregnancy Outcome in Women with Polycystic Ovarian Syndrome with Sub Fertility
%A Afroza Kutubi
%A Ashia Khatun
%A Hasina Begum
%A Israt Jahan
%A Khairun Nahar
%A Tahmina Hassan
%J Journal of Shaheed Suhrawardy Medical College
%D 2017
%R https://doi.org/10.3329/jssmc.v9i1.37250
%X Background: Anti-mullerian hormone (AMH) in largely expressed throughout folliculogenisis (by granulosa cells in ovarian follicles) but highest in pre-antral and small antral steges (<4mm) drameter of development. Objective: To analyse the usefulness of plasma anti-mullerian hormone (AMH) measurement as a test for assessing ovarian reserve in Polycystic ovary syndrome with sub fertility, Methodology: Women with PCOS and sub fertility, were included in this study with age group 18-35yrs. This Prospetive cohort study done in 30 cases in ShSMC with purposive randomized sampling, from January 2015 to December 2015. Serum, plasma & for evaluation of PCOS, preferably TV-USG was done. Result: In this study we analyze 30 serum samples from patient aged between 18-35 years and transvaginal ultrasonography was done simultaneously. Mean age group of my patient was 25.2¡À4.7 years which correlates with AMH level in PCOS which is statistically significant (p<0.001). Mean level of AMH is 5.7¡À4.9 mg/ml which is also correlate with transvaginal USG scan with the feature of PCOS (p<.0.001). More than 50% woman presents with features of subfertility with PCOS and 46.7% are normal ovaries. Mean menstrual day 7.6 (4-12 days) which have a good linear correlation with irregularities of menstrual cycle and PCOS (p<0.05). Conclusion: To conclude AMH appears to have a major inhibiting role during folliculogenesis, which may contribute to anovulation in PCOS. The reason for the raised AMH in PCOS may give clues as to the mechanism os anovulation. J Shaheed Suhrawardy Med Coll, June 2017, Vol.9(1); 3-5
%K Infertility
%K PCOS
%K anti-mullerian hormone
%K (Obs & Gynae)
%K OPD
%U https://www.banglajol.info/index.php/JSSMC/article/view/37250