%0 Journal Article
%T Protective Effect of Cocoa Extract on Malondialdehyde Level in Ultraviolet B Induced - Albino Mice Skin
%J -
%D 2017
%X The antioxidant activity in cocoa linked to the polyphenol content therein, especially subunit monomers catechin and epicatechin. The aim of the study was to determine the protective effects of cocoa extract on levels of malondialdehyde in albino mice by exposure to UVB. This study was conducted at animal laboratory to interventions UVB and Extract, Cocoa and Biomolecular laboratory of medical faculty of Hasanuddin University for the ELISA examination. This study used true experimental design with animal experimental design to assess the effectiveness of topical application cacao extract on mice skin after UVB induction for twelve weeks. The research samples were 30 head of albino mice divided into 6 groups: control 5 mice without protection and given 450 mJ UV Bexposure 3 times per week, the second group was 5 untreated controlmice, the third group was 5 mice with 100 ppm of cocoa topical extract every day and UVB 450 mJ exposure 3 times a week, the fourth group of 5 mice with 200 ppm topical cocoa extract every day and exposure to 450 mJ three times a week, the fifth group of 5 mice with 400 ppm topical cocoa extract every day and exposure to 450 mJ three times a week, the sixth group of 5 mice with 800 ppm topical everyday cocoa extract and exposure to 450 mJ three times a week, a week after termination and biopsy excisionof skin for examination of Malondialdehyde level with ELISA. The results indicated resources of 200 ppm cocoa extract Provides the best effect with reduced MDA levels with the highest protective effect Compared to other groups.
%K Cocoa Extract
%K Malondialdehyde
%K Ultraviolet B
%U http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=254&doi=10.11648/j.ajcem.20170502.13