%0 Journal Article
%T Efficacy of a Daily Protective Moisturizer with High UVB and UVA Photoprotection in Decreasing Ultraviolet Damage: Evaluation by Reflectance Confocal Microscopy
%A Antonio Gomes-Neto
%A Cristina Carrera
%A Dominique Moyal
%A Josep Malvehy
%A Leonor Prieto
%A Paula Aguilera
%A Sophie Seit¨¦
%A Susana Puig
%J -
%@ 1651-2057
%D 2017
%R 10.2340/00015555-2736
%X Patients with photodermatoses or actinic keratosis benefit from very high ultraviolet B-ultraviolet A (UVB-UVA) photoprotection. However, poor compliance is an issue that jeopardizes adequate protection, leading to disease recurrence. This study evaluated the efficacy of a daily protective moisturizer with high UVB and UVA photoprotection applied 8 h before irradiation. A monocentric, open-label, prospective, control pilot study was performed including 10 patients. Patients were irradiated with UVB and UVA before and 8 h after topical application of the product. Reflectance confocal microscopy (RCM) assessment was performed 24 h later. Clinical assessment showed a statistically significant increase in minimal erythema dose (MED) after application of the product (p£¿<£¿0.001). Signs of UV damage according to RCM were not observed on photoprotected skin (p£¿<£¿0.05). Skin irradiated 8 h after applying a daily protective moisturizer presented an increase in MED and RCM findings that equal the findings for non-irradiated skin
%U http://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-2736