%0 Journal Article
%T Combined Fractional Treatment of Acne Scars Involving Non-ablative 1,550-nm Erbium-glass Laser and Micro-needling Radiofrequency: A 16-week Prospective, Randomized Split-face Study
%A Chanhee Kang
%A Gyeong-Hun Park
%A Hae Young Park
%A Hyuck Hoon Kwon
%A Jae Yoon Jung
%A Sun Chul Choi
%A Youin Bae
%J -
%@ 1651-2057
%D 2017
%R 10.2340/00015555-2701
%X An optimized therapeutic regimen involving a non-ablative fractionated laser or radiofrequency therapy for acne scars has not yet been established. To evaluate whether the combination of a non-ablative fractional laser (NAF) and fractional micro-needling radiofrequency (FMR) has clinical advantages for the treatment of atrophic acne scars compared with NAF alone, a 16-week prospective, randomized split-face study was performed. Each facial side of a patient was treated with 3 sessions of either NAF with FMR or NAF alone, with a 4-week interval between each session. Although both sides demonstrated significant decreases in the ¨¦chelle d¡¯¨¦valuation clinique des cicatrices d¡¯acn¨¦ (ECCA) score, the facial side treated using the combination regimen demonstrated greater improvement in ECCA score regarding degree and onset time than the NAF-treated side. Histopathological and immunohistochemical results confirmed the clinical findings. This study demonstrated that a combination regimen involving NAF and FMR could be a viable option with satisfactory efficacy.
%U http://www.medicaljournals.se/acta/content/abstract/10.2340/00015555-2701