%0 Journal Article %T Evaluation of Eimeria oocyst whole antigen vaccine and the enhancive effect of probiotic on broilers %A Ahmed ElKhatam %A Mahmoud AbouLaila %A Nasr ElBahy %A Reda Khalafalla %J - %D 2014 %R 10.14419/ijbas.v3i4.3109 %X Chicken coccidiosis has great economic impacts on poultry industry. The present study was conducted to evaluate the effect of feeding probiotic (Biopellt-s) as well as Eimeria oocyst whole antigen vaccine by subcutaneous and intraperitoneal routes on body weight gain, lesion score, oocyst output, and phagocytic activity. One-day old broiler chicks were divided into seven equal groups (50 chicks each); control negative group (C-Ve), probiotic fed group (PRO), subcutaneous vaccinated group (S/C), intraperitoneal vaccinated group (I/P), S/C plus probiotic (S/C Pro), I/P plus probiotic (I/P Pro), and positive control group (C+Ve). At four weeks, chicks challenged with 12.000 sporulated oocysts. Vaccination decreases the lesion score and the oocyst output in S/C group (9000 oocyst/gram) and in I/P group (12500 oocyst/gram) compared with positive control (43500 oocyst/gram). S/C was more effective than I/P for controlling the infection. Probiotic supplementation resulted in significant increase in body weight gain (1323 gm) compared with positive control (1026.667 gm) and phagocytic activity (22.83 %) compared with positive control (16.08 %) while the vaccination was more effective than probiotic alone. S/C vaccination with probiotic was more effective than with I/P vaccination. Therefore, this study recommends the use of S/c or I/P vaccination regimens for coccidiosis. Keywords: Chicken Coccidiosis, Eimeria Oocyst Whole Antigen Vaccine, Probiotic. %U https://www.sciencepubco.com/index.php/ijbas/article/view/3109