%0 Journal Article
%T Evaluation of Red Cell Distribution Width and Platelet Indices in Children with Chronic Heart Disease
%A Hanan F. Hussein
%A Eglal H. Al-Gohary
%A Amal G. Mohamed
%A Amal A. A. Abd El-Salam
%J Open Journal of Pediatrics
%P 78-99
%@ 2160-8776
%D 2021
%I Scientific Research Publishing
%R 10.4236/ojped.2021.111008
%X <strong>Background:</strong><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> Platelets play a key role in the development and progression of
cardiovascular diseases. Also red cell distribution width (RDW%) &amp; platelet
indices are a good predictor of clinical outcomes.</span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Purpose: </span></b></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\">Study the relationship between RDW%, platelets count, mean platelet
volume (MPVfl) and platelet distribution width (PDWfl) in children with
congenital heart disease </span><span style=\"font-family:Verdana;\">(CHD) or rheumatic
heart diseases (RHD).</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Subjects and Methods:</span></b></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"> The</span></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> study
was carried on 151 children diagnosed as CHD or RHD selected from pediatric
department of Al-Zahraa University Hospital and National Heart Insti</span><span style=\"font-family:Verdana;\">tute. They were aged from 6 months to 12 years.
Another 80 apparently</span><span style=\"font-family:Verdana;\"> healthy children were taken as controls. Complete
blood count and echocardiography examination were evaluated for all
participants.</span></span></span></span><span><span><span style=\"font-family:&quot;\"> </span></span></span><span style=\"font-family:Verdana;\"><span style=\"font-family:Verdana;\"><b><span style=\"font-family:Verdana;\">Results:</span></b></span></span><span><span><span style=\"font-family:&quot;\"><span style=\"font-family:Verdana;\"> The mean value of </span><span style=\"font-family:Verdana;\">RDW% was increased
in CHD and RHD than controls, RDW% higher in</span><span style=\"font-family:Verdana;\"> cyanotic CHD (CCHD) (either
decompensated or compensated) than acyanotic CHD, and in decompensated RHD than
compensated RHD with more than one valve affection. The mean platelets count
were decreased in cyanotic than acyanotic CHD, platelets count were increased
in
%K Congenital
%K Disease
%K Heart
%K Platelet Indices
%K Red Cell
%K Distribution Width
%K Rheumatic Heart Diseases
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=107615