%0 Journal Article
%T 低温停循环主动脉夹层术后患者院内死亡的术中危险因素分析
%A 宋海成　吕琳　柳国强　夏婧　王君涛　张楠楠　袁莉
%J -
%D 2019
%R 10.13362/j.jpmed.201906005
%X 摘要 目的　探讨低温停循环下主动脉夹层术中相关因素与患者院内死亡之间的关系。 方法　回顾性分析青岛大学附属医院198例低温停循环下主动脉夹层患者手术资料，包括术前患者一般资料、术中低温停循环期间相关指标和乳酸增高率。采用Logistic回归模型分析患者术后院内死亡的危险因素。 结果　患者院内病死率为19.8％。在Logistic回归模型中，体质量（OR=1.034，95％CI=1.004～1.069，P＜0.05），术中失血量（OR=1.371，95％CI=1.088～1.726，P＜0.01）和乳酸增高率（OR=3.367，95％CI=1.786～7.406，P＜0.01）是患者院内死亡的危险因素。 结论　低温停循环主动脉夹层术中的乳酸增高率、体质量、术中失血量与主动脉夹层患者术后院内死亡密切相关。<br>Abstract：Objective　To investigate the association of related factors during surgery for aortic dissection under hypothermic circulatory arrest (HCA) with in-hospital death. Methods　A retrospective analysis was performed for the clinical data of 198 patients with aortic dissection who underwent surgery under HCA in The Affiliated Hospital of Qingdao University, including general information, related intraoperative indices during HCA, and lactate increase rate. A logistic regression analysis was used to investigate the risk factors for in-hospital death after surgery. Results　The in-hospital mortality rate was 19.8%. The logistic regression analysis showed that body weight (OR=1.034,95%CI=1.004-1.069,P<0.05), intraoperative blood loss (OR=1.371,95%CI=1.088-1.726,P<0.01), and lactate increase rate (OR=3.367,95%CI=1.786-7.406,P<0.01) were risk factors for in-hospital death. Conclusion　Lactate increase rate, body weight, and intraoperative blood loss are associated with in-hospital death in patients undergoing surgery for aortic dissection under HCA
%K 停循环
%K 深低温诱导
%K 动脉瘤
%K 夹层
%K 乳酸
%K 医院病死率
%K 危险因素<br>Circulatory arrest
%K deep hypothermia induced
%K Aneurysm
%K dissecting
%K Lactic acid
%K Hospital mortality
%K Risk factors
%U http://jpmed.qdu.edu.cn/CN/10.13362/j.jpmed.201906005