%0 Journal Article
%T A Comparative Study on Evaluation of In vitro Cytotoxic Activity of Ipomoea pes-caprae and Murraya koenigii
%A Mahadi Hassan
%A Mohammad Mobarak Hossain
%A Rumpa Bhowmic
%A Sayed Koushik Ahamed
%J -
%D 2014
%X The purpose of the research is to find out the comparative cytotoxic potentials of Ipomoea Pes-Caprae and Murraya koenigii fractions (crude methanol, Pet ether, Chloroform) by using brine shrimp mortality assay. These two plant extracts were tested at concentration 400, 200, 100, 50, 25, 12.5, 7.25, 3.125 ¦Ìg/ml. The extracts of both plants showed remarkable cytotoxic activity. Following, the ascertainment of  LC50 values of the extracts  (crude, Chloroform, pet ether) the extracts of  Ipomoea Pes-Caprae (1.649,5.691, 1.583 ¦Ìg/ml) and Murraya koenigii( 4.365, 10, 5.370 ¦Ìg/ml) were respectively compared to a reference drug vincristin sulphate with LC50 0.839 ¦Ìg/ml. Ipomoea Pes-Caprae  was determined as more cytotoxic than Murraya koenigii. Where chloroform extract of Murraya koenigii showed low cytotoxicity than all the extract of Ipomoea Pes-Caprae
%K Mohammad Mobarak Hossain
%K Mahadi Hassan
%K Arif Istiaq
%K Rumpa Bhowmic and Sayed Koushik Ahamed
%K LC50
%K Cytotoxic potential
%K Ipomoea Pes-Caprae
%K Murraya koenigii
%K Vincristin sulphate
%K Fractions
%K Extracts
%U https://www.imedpub.com/abstract/a-comparative-study-on-evaluation-of-in-vitro-cytotoxic-activity-of-ipomoea-pescaprae-and-murraya-koenigii-10621.html