%0 Journal Article
%T The Potential of Non-Invasive Biochemical Testing Late Post-transplant in Prediction of Declining Kidney Allograft Function
%A Nykonenko O
%A Trailin A
%J -
%D 2017
%X Identification of kidney transplant recipients at risk for allograft failure late posttransplant is an unmet demand. Our aim was to determine the capacity of serum beta-2- microglobulin (2MG), serum and urinary interleukins (IL-2, IL-10 and IL-8) and enzymes (¦Ã-glutamyl transpeptidase, alkaline phosphatase, alanine aminotransferase [ALT], aspartate aminotransferase [AST], and N-acetyl-¦Â-Dhexosaminidase [NAG]) in the late posttransplant period to predict a deterioration of kidney allograft function. Several non-invasive biomarkers predicted certain (serum 2MG, urinary IL-2 and AST), and rapid (urinary IL-2 and AST) drop of glomerular filtration rate over two years. We are standing on underestimated potential of non-invasive biochemical testing in kidney transplant setting.
%K Kidney transplant
%K Allograft
%K Aminotransferase
%K Kidney
%K list of open access journals
%K open access
%K open access journals
%K open access publication
%K open access publisher
%K open access publishing
%K open access journal articles
%K imedpub
%K imedpub publishing
%K insight medical publishing
%K imedpub online
%U https://www.imedpub.com/articles/the-potential-of-noninvasive-biochemical-testing-late-posttransplant-in-prediction-of-declining-kidney-allograft-function.php?aid=20873