%0 Journal Article
%T Role of Tumor necrosis factor alpha, Malondialdehyde & serum Iron in Anemic Tuberculosis Patients
%A Ajit Deshp
%A Akhouri R Sinha4
%A Meena Verma. Ravi Saxena
%A Rashmi kulkarni
%A e
%J -
%D 2011
%X The role of Tumor Necrosis Factor alpha, Malondialdehyde and serum Iron in inducing anemia in Tuberculosis patients was studied. The present study was conducted in the De-partment of Biochemistry, Shri Aurobindo Institute of Medical Sciences, Indore. The study comprised of sixty-eight anemic pulmonary tuberculosis patients. Levels of Hemoglobin, Iron, TIBC, Ferritin, MDA & TNF ¦Á were analyzed in all of them. The inflammatory pa-rameters TNF ¦Á & Ferritin along with oxidative marker malondialdehyde were found to be increased in anemic tuberculosis patient and levels of Hb, iron & TIBC was decreased. Overall correlation shows that the levels of Hb, Iron & TIBC were negatively correlated to the levels of Ferritin, MDA & TNF ¦Á. Ferritin was negatively correlated with Iron (r = -0.261, p<0.05) & showed a positive correlation with MDA. (r = 0.304, p < 0.05). For Ferritin & TNF ¦Á correlation was positive, it was not significant (r = 0.114, NS).There was a positive significant correlation between Iron & TIBC. (r = 0.666, p<0.01) & a negative significant correlation between the TNF ¦Á levels and the hemoglobin concentration (r = -.273, p<0.05). Hypoferremia was induced as a consequence of inflammatory response and action of free radicals in anemic tuberculosis patient
%K Anemia
%K Hypoferremia
%K Ferritin
%K TNF £¿£¿£¿¡À
%K Malondialdehyde
%U https://www.alliedacademies.org/articles/role-of-tumor-necrosis-factor-alpha-malondialdehyde--serum-iron-in-anemic-tuberculosis-patients.html