%0 Journal Article
%T Botulinum toxin type-A overdose for the treatment of spastic muscles in two patients with brain injuries
%A Guangtao Bai
%A Jiang Li
%A Ru Zhang
%A Xia Chen
%A Xiaoyan Xu
%A Yifeng Du
%J -
%D 2017
%X Spasticity is commonly encountered clinically, and always affects patients¡¯ motor ability and capacity for self-care which necessitates intervention. At present, numerous methods have been proposed with varying effects. Many reports show that the most effective method is to inject botulinum toxin, type A (BTX-A) into the spasming muscles, but the doses are different. The guidline of BTX-A injection in Chinese adults is restricted to 600 IU each time within 3 months. In this article, we treated two brain injury patients with severe regional spasticity with overdose of China-making BTX-A whose trademark is HengLi. The treatment improved spasticity and with little adverse effects. We therefore conclude that overdoses of BTX-A could also be safe and more efficient used in some patients who are showing severe spasticity of limb muscles, but it should be vary with each individual and a large sample size trial is needed for a further confirmation
%K Botulinum toxins
%K Type A
%K Brain injuries
%K Injections
%K Drug overdose
%U https://www.alliedacademies.org/articles/botulinum-toxin-typea-overdose-for-the-treatment-of-spastic-muscles-in-two-patients-with-brain-injuries.html