%0 Journal Article
%T Fatal gastrointestinal bleeding and perforated duodenal ulcer: a rare complication of deferasirox in a patient with liver cirrhosis
%A Ayse Salihoglu
%A Ibrahim Hatemi
%A Kadri Atay
%A Tugce Eskazan
%J -
%D 2017
%X We report here a case of deferoxamine (DFX) related gastrointestinal bleeding and duodenal perforation in a cirrhotic patient after the use of deferasirox for secondary hemochromatosis. Duodenal ulcer bleeding and perforation is noted as a rare adverse event in the scientific product information of deferasirox, in our current knowledge, this is the first case-report on this adverse drug reaction at adult patients. Clinicians must be aware that deferasirox use in a cirrhotic patient may have a potential risk of complicated gastrointestinal ulceration. It is recommended that patients undergoing treatment with deferasirox especially with liver cirrhosis are monitored regularly for adverse events
%K Gastrointestinal bleeding
%K Duodenal ulcer
%K Deferasirox
%K Liver cirrhosis
%U https://www.alliedacademies.org/articles/fatal-gastrointestinal-bleeding-and-perforated-duodenal-ulcer-a-rare-complication-of-deferasirox-in-a-patient-with-liver-cirrhosis.html