%0 Journal Article %T Anti-osteosarcoma effect of novel pyran-annulated heterocycles derivatives %A Li Cao %A Qing Bi %A Wei-Wei Ruan %A You-Jia Xu %J - %D 2017 %X The synthesis and characterization of four novel pyran derivatives (1-4) were realized by means of IR, 1H NMR, HRMS, and single crystal X-ray crystallography. The anti-osteosarcoma activities of the four compounds were investigated against three human osteoma sarcomatosum cells (HuO9, 143B and MG-63) by MTT assay. It has been found that compounds 3 and 4 exerted much more potent activities against the three cell lines than the other two compounds %K Pyran %K Crystal %K Anti-osteosarcom %U https://www.alliedacademies.org/articles/antiosteosarcoma-effect-of-novel-pyranannulated-heterocycles-derivatives.html