%0 Journal Article
%T Evaluation of the relationship between thromboembolic risk score (CHA2DS2-VASc) and inflammation and coagulation markers in patients with non-valvular atrial fibrillation in emergency department.
%A Birol Civelek
%A Bunyamin Yavuz
%A Fatih Nazmi Yaman
%A Mehmet Cagri Goktekin
%A Metin Atescelik
%A Mustafa Sahan
%A Mustafa Yilmaz
%J -
%D 2016
%X Objective: To evaluate the relationship between CHA2DS2-VASc score and inflammation and coagulation markers in patients admitted to Emergency Department (ED) with non-valvular Atrial Fibrillation (AF).
Methods and Results: Eighty-four patients with non-valvular AF were included in the study. CHA2DS2- VASc scores were calculated for these patients. In addition, plasma levels of BNP, hs-CRP, CRP, vWF and D-dimer were measured. The relationship between CHA2DS2-VASc score and these parameters were evaluated. Eleven (13%) patients were considered to be at low-risk due to CHA2DS2-VASc score being<2 and 73 (87%) patients were considered to be at high risk due to CHA2DS2-VASc score being ¡Ý 2. The mean age of patients was 68 ¡À 13 years and 50 (60%) of patients were male. Plasma BNP, hs-CRP, CRP, vWF and D-dimer levels were significantly higher in high-risk group. In addition, a significant positive correlation was found between CHA2DS2-VASc score and BNP (r=0.436, p<0.001), D-Dimer (r=0.356, p=0.003), hs-CRP (r=0.335, p=0.002), CRP (r=0,331, p=0.002), vWF (r=0.330, p=0.002) and patient age (r=0.573, p<0.001).
Conclusion: It was found that BNP, hs-CRP, CRP, vWF and D-dimer levels increase significantly and that there is a positive correlation between CHA2DS2-VASc and these markers in high-risk patients with CHA2DS2-VASc score ¡Ý 2
%K Atrial fibrillation
%K BNP
%K CHA2DS2-VASc score
%K D-Dimer
%K hs-CRP
%K vWF
%U https://www.alliedacademies.org/articles/evaluation-of-the-relationship-between-thromboembolic-risk-score-cha2ds2vasc-and-inflammation-and-coagulation-markers-in-patients-.html