%0 Journal Article
%T Neurofibromatosis and type-1 diabetes in a seven-year-old child: A rare
combination.
%A Abdulmoein Eid Al-Agha
%A Amal Zaki
%A Atheer Asiri
%J -
%D 2018
%X Neurofibromatosis type 1 (NF1) can occur along with other autoimmune diseases. We report the case of a child with coexisting neurofibromatosis and type 1 diabetes mellitus. A seven-year-old Yemeni girl, who was diagnosed with neurofibromatosis type 1 at birth, presented at the age of two months with her first episode of diabetic ketoacidosis. Further lab investigations during her follow-up sessions showed a decreased level of growth hormone. Abnormal neurofibromin production is the main pathophysiology of neurofibromatosis that contributes to an increased susceptibility to tumors and other coexisting autoimmune diseases; this requires further discussion. This is, to the best of our knowledge, the third case reported to have this rare combination of a de novo mutation causing NF1 and an autoimmune disease, which is type 1 diabetes mellitus
%K Neurofibromatosis
%K Type 1 diabetes
%K Children
%K Association
%K Autoimmune
%U https://www.alliedacademies.org/articles/neurofibromatosis-and-type1-diabetes-in-a-sevenyearold-child-a-rarecombination-10478.html