%0 Journal Article
%T Comparison of Different Adrenergic Blockers on Cutaneous Wound Healing in Wistar rats
%A Anil K Mahapatra & Rajdip L Vaishnav
%A Manohar R Amaresh Parimi
%A Veena Nayak
%J -
%D 2014
%X Background: This study was undertaken to evaluate & compare the effect of nonselective ¦Â-blocker, ¦Á-blocker and ¦Á+¦Â blocker on excision wounds in animal models. Methods: Animals with excision wound models were divided into six groups (n=6) and  were administered  vehicle, propranolol 1% , propranolol 2%, carvidelol 2%, carvidelol 5% and phentolamine 2% ointments topically respectively daily for 21 days.  Contraction was noted every alternate day and wound area was determined. Wound contraction (WC) was also calculated. Results: Carvedilol 5%, propranolol 1% and propranolol 2% significantly increased percentage of wound contraction (p ¡Ü 0.05) as compared to phentolamine. In comparison to carvedilol 5%, propranolol 1% was superior. Conclusion: ¦Â-blocker are superior to ¦Á- blockers in the process of wound healing
%K Veena Nayak
%K Bharti Chogtu
%K Manohar R Amaresh Parimi
%K Anil K Mahapatra & Rajdip L Vaishnav
%K Excision wound healing
%K Propranolol
%K Carvedilol
%K Phentolamine
%U https://www.imedpub.com/abstract/comparison-of-different-adrenergic-blockers-on-cutaneous-wound-healing-in-wistar-rats-10656.html