%0 Journal Article
%T Reversed phase high performance liquid chromatography method for determination of Thiocolchicoside from active pharmaceutical dosage form
%J -
%D 2015
%X A simple, rapid and accurate high performance liquid chromatography method is described for determination of thiocolchicoside from active pharmaceutical ingredients. The separation of drug was achieved on Zorbax Eclipse C18 (250 x 4.6 mm i.d.) with 5 ¦Ì particle size column showed most favorable chromatographic pattern over the other columns. The mobile phase consisted of a mixture of buffer and acetonitrile (70:30 % v/v). The buffer was mixtures of 0.1 % tri-ethyl amine adjusted the pH 3.3 with ortho-phosphoric acid. The detection was carried out at wavelength 260 nm. The mixture of buffer and acetonitrile (70:30% v/v) was used as a diluent. The method was validated for system suitability, linearity, accuracy, precision, robustness, stability of sample solution. The method has been successfully used to analyze thiocolchicoside hydrochloride from active pharmaceutical ingredient
%K Rajan V.Rele
%K Thiocolchicoside
%K Acetonitrile
%K tri-ethyl amine
%U https://www.imedpub.com/abstract/reversed-phase-high-performance-liquid-chromatography-method-for-determination-of-thiocolchicoside-from-active-pharmaceutical-dosage-form-11851.html