%0 Journal Article
%T Total and Cardiovascular Mortality Risk Associated with Allergic Rhinitis and
Allergic Asthma: A Retrospective Cohort Study
%A Evans E
%A Faramawi MF
%A Felini M
%A G
%A hi S
%J -
%D 2016
%X Title: Total and Cardiovascular Mortality Risk Associated   with Allergic Rhinitis and Allergic Asthma: A Retrospective   Cohort Study
Background: Asthma and allergic rhinitis are two major   respiratory conditions of public health concern   worldwide. These conditions are also identified as risk   factors for atherosclerosis, a contributor of cardiovascular   outcomes. Our objectives were to investigate the   independent and concomitant role of allergic rhinitis and   asthma on cardiovascular and all-cause mortality.
Methods and findings: The study participants consisted of   a probability sample of US civilians from the Third   National Health and Nutrition Examination Survey; vital   status was ascertained through the National Death Index.   Men and women ¡Ý40 years from all racial/ethnic   backgrounds were included in the study. For all-cause   mortality (n=9,450) and CVD-specific mortality (n=9,410),   the baseline characteristics of participants were similar   except for age, education, and smoking status. For both   the outcomes, hazard ratios were estimated using Cox regression models.
Risk for all-cause mortality increased for those with   histories of allergic rhinitis [HR: 1.08 (95%: 0.91-1.29)],   and asthma [HR: 1.36 (95%: 1.00-1.89)] whereas risk for   CVD-specific mortality showed null association for those   with histories of allergic rhinitis [HR: 1.00 (95%:   0.75-1.31)], with elevated risk for those with asthma [HR:   1.32 (95%: 0.85-2.06)]. The combined effect of allergic   rhinitis and asthma showed increased risk for all-cause   mortality [HR: 1.23 (95%: 0.91-1.29)] and CVD-specific   mortality [HR: 1.66 (95%: 0.85-3.25)].
Conclusion: Our study provides preliminary evidence of   the independent and concurrent association between   allergic rhinitis and asthma and all-cause and CVD-specific   mortality
%K Gandhi S
%K Faramawi MF
%K Aryal S
%K Evans E and Felini M
%K Asthma
%K Allergic rhinitis
%K Bronchitis
%K Immunoglobulins
%U https://www.imedpub.com/abstract/total-and-cardiovascular-mortality-risk-associated-with-allergic-rhinitis-andrnallergic-asthma-a-retrospective-cohort-study-17796.html