%0 Journal Article
%T <i>In vitro</i> anti-microbial activity of some 2-(substituted)amino-5-aryl-
1,3,4-thiadiazoles
%A Pradeep Mishra
%A Sanmati K. Jain
%J -
%D 2011
%X In vitro anti-microbial activity of the 28 synthesized compounds [2-(Substituted)amino-5-aryl-
  1,3,4-thiadiazoles)] was carried out by Liquid dilution method. For antibacterial study three
  Gram negative strains i.e., Proteus mirabilis (MTCC 425), Shigella flexneri (MTCC 1457),
  Pseudomonas aeruginosa (MTCC 424) and two Gram positive strains i.e., Staphylococcus
  aureus (MTCC 96) and Bacillus subtilis (MTCC 619) were taken. For antifungal study
  Aspergillus niger (MTCC 1344) and Candida albicans (MTCC 227) were used. Results indicate
  that compounds studied for anti-bacterial and anti-fungal activity, appreciable activity was
  shown by compounds 24, 10, 11 and 2 against P. aeruginosa i.e., 24, 36, 54 and 58 ¦Ìg/ml
  concentrations (MIC) respectively. In addition compound 2, 3, 17, 9, 10 and 11 showed activity
  against S. flexneri. Compound 20 showed activity against P. mirabilis. Compound 24 and 26
  showed activity against B. subtilis. It was observed that none of the compounds inhibit the
  growth of the bacterial strain S. aureus. None of the compounds showed any anti-fungal activity.
%K 1
%K 3
%K 4-thiadiazoles
%K Anti-microbial activity
%K list of open access journals
%K open access
%K open access journals
%K open access publication
%K open access publisher
%K open access publishing
%K open access journal articles
%K imedpub
%K imedpub publishing
%K insight medical publishing
%K imedpub online
%U https://www.imedpub.com/articles/iin-vitroi-antimicrobial-activity-of-some-2substitutedamino5aryl134thiadiazoles.php?aid=11884