%0 Journal Article
%T Evaluation of antibacterial properties of nano silver Iranian MTA against Fusobacterium nucleatum
%A Abbas Bahador
%A Azad Khaledi
%J -
%D 2013
%X The purpose of this study is to evaluate the antimicrobial effect of Iranian mineral trioxide aggregate (IMTA) and NanoSilver¨CIMTA (NS¨CIMTA) at clinical concentrations against Fusobacterium nucleatum, a Gram-negative anaerobic bacterium, which is one of the most prevalent taxa in the infected apical root canal system, chronic suppurative apical periodontitis and endodontic flare-ups. We combined NS (0.1 mg/mL) with IMTA at 3, 6 and 12% concentrations. To evaluate the antimicrobial effect, agar diffusion and broth dilution methods were used. In the agar diffusion test, IMTA and NS¨CIMTA showed zones of inhibition against F. nucleatum. The MIC of NS was 0.003 mg/mL. In broth dilution assay, IMTA reduced the growth of F. nucleatum by 71.3% and 88.9% after 48 h and 72 h, respectively. For 3% NS IMTA, the reduction in the number of viable bacteria was as the same as IMTA after 72 h. IMTA containing 6% and 12% NS completely inhibited the proliferation of F. nucleatum. A statistically significance difference (P<0.05) was found between IMTA and IMTA containing 6% and 12% of NS. In conclusion, NS¨CIMTA could completely inhibit the proliferation of F. nucleatum in dose-dependent manner that may have a significant effect in prognosis of root perforation
%K Abbas Bahador
%K Azad Khaledi and Roghayeh Ghorbanzadeh
%K Antimicrobial Agents
%K Fusobacterium nucleatum
%K MTA
%K Silver Nanoparticles
%U https://www.imedpub.com/abstract/evaluation-of-antibacterial-properties-of-nano-silver-iranian-mta-against-fusobacterium-nucleatum-15633.html