%0 Journal Article
%T Novel acrylic copolymers derived from Paracetamol: Determination
of reactivity ratio, microbial screening and thermal properties
%A Jignesh B. Dholakiya1
%A Kirit H. Patel1
%A Rajni M. Patel2
%J -
%D 2011
%X The monomer p-acetamidophenyl methacrylate (PAPM) has been synthesized by reacting paracetamol with methacryloyl chloride using methanol as solvent. Homopolymers of PAPM, quinoline methaacrylate (QMA) and its copolymers were synthesized by free radical polymerization technique using 2,2ˇŻ-azobisisobutyronitrile (AIBN) as an initiator with different monomer-to-monomer ratios in the feed. The prepared copolymers were characterized by FT-IR spectroscopy. The copolymer composition was evaluated by 1H-NMR and was further used to determine reactivity ratios. The monomer reactivity ratios for PAPM (M1)-QMA (M2) pair were determined by using Fineman-Ross (F-R) (r1 =0.66; r2 =1.12), Kelen-Tudos (K-T) (r1 = 0.66; r2 = 1.12) and extended Kelen-Tudos (Ex.K-T)(r1 = 0.65; r2 = 1.13) methods. Thermogravimetry analysis (TGA) showed that thermal decomposition of the polymer occurred in a two step. The first step decomposition occurs in the ranges from 224ˇăC to 350ˇăC whereas second step ranges from 350ˇăC to 503ˇăC. TGA data also showed that activation energy of all poly(PAPM-co-QMA) are in range of 38-52 K.J.mole-1.The values of integral procedural decomposition temperature (IPDT) calculated by DoyleˇŻs method for copolymers is in the range of 379ˇăC -389ˇăC. Activation energies (Ea) calculated by BroidoˇŻs method are in the range of 41-52 K.J.mole-1 for poly(PAPM-co-QMA). The characteristic temperature and kinetic parameters for the homo and copolymers have been obtained from DTA traces using ReichˇŻs method. The molecular weights of the polymers were determined using gel permeation chromatography. All polymers were tested for their antimicrobial property against various microorganisms and found to possess significant antimicrobial activity. The composition of copolymers can be regulated to have materials of desired property
%K Jignesh B. Dholakiya1
%K Hetal J. Patel1
%K Kirit H. Patel1 and Rajni M. Patel2
%K copolymers
%K reactivity ratio
%K thermal analysis
%K antimicrobial properties
%U https://www.imedpub.com/abstract/novel-acrylic-copolymers-derived-from-paracetamol-determinationrnof-reactivity-ratio-microbial-screening-and-thermal-properties-12721.html