%0 Journal Article
%T ¦Â-Adrenoreceptor agonists in the management of pain associated with renal colic: a systematic review
%A Andrew John Tabner
%A Apostolos Fakis
%A Graham David Johnson
%A Jane Surtees
%A Robert Iain Lennon
%J -
%D 2016
%R 10.1136/bmjopen-2016-011315
%X Objectives To determine whether ¦Â-adrenoreceptor agonists are effective analgesics for patients with renal colic through a systematic review of the literature.

Setting Adult emergency departments or acute assessment units.

Participants Human participants with proven or suspected renal colic.

Interventions ¦Â-adrenoreceptor agonists.

Outcome measures Primary : level of pain at 30£¿min following administration of the ¦Â-agonist. Secondary : level of pain at various time points following ¦Â-agonist administration; length of hospital stay; analgesic requirement; stone presence, size and position; degree of hydronephrosis.

Results 256 records were screened and 4 identified for full-text review. No articles met the inclusion criteria.

Conclusions and implications There is no evidence to support or refute the proposed use of ¦Â-agonists for analgesia in patients with renal colic. Given the biological plausibility and existing literature base, clinical trials investigating the use of ¦Â-adrenoreceptor agonists in the acute setting for treatment of the pain associated with renal colic are recommended.

Trial registration number CRD42015016266
%U https://bmjopen.bmj.com/content/6/6/e011315