%0 Journal Article %T The Olympic Regeneration in East London (ORiEL) study: protocol for a prospective controlled quasi-experiment to evaluate the impact of urban regeneration on young people and their families %A Adrian Renton %A Amanda E Fahy %A Charlotte Clark %A Claire Thompson %A Daniel J Lewis %A Derek G Moore %A Kamaldeep S Bhui %A Mark Petticrew %A Neil R Smith %A Sandra Eldridge %A Stephanie J C Taylor %A Stephen A Stansfeld %A Steven Cummins %A Tricia Greenhalgh %A Vanathi Tharmaratnam %J - %D 2012 %R 10.1136/bmjopen-2012-001840 %X Introduction Recent systematic reviews suggest that there is a dearth of evidence on the effectiveness of large-scale urban regeneration programmes in improving health and well-being and alleviating health inequalities. The development of the Olympic Park in Stratford for the London 2012 Olympic and Paralympic Games provides the opportunity to take advantage of a natural experiment to examine the impact of large-scale urban regeneration on the health and well-being of young people and their families. Design and methods A prospective school-based survey of adolescents (11¨C12£¿years) with parent data collected through face-to-face interviews at home. Adolescents will be recruited from six randomly selected schools in an area receiving large-scale urban regeneration (London Borough of Newham) and compared with adolescents in 18 schools in three comparison areas with no equivalent regeneration (London Boroughs of Tower Hamlets, Hackney and Barking & Dagenham). Baseline data will be completed prior to the start of the London Olympics (July 2012) with follow-up at 6 and 18£¿months postintervention. Primary outcomes are: pre¨Cpost change in adolescent and parent mental health and well-being, physical activity and parental employment status. Secondary outcomes include: pre¨Cpost change in social cohesion, smoking, alcohol use, diet and body mass index. The study will account for individual and environmental contextual effects in evaluating changes to identified outcomes. A nested longitudinal qualitative study will explore families¡¯ experiences of regeneration in order to unpack the process by which regeneration impacts on health and well-being. Ethics and dissemination The study has approval from Queen Mary University of London Ethics Committee (QMREC2011/40), the Association of Directors of Children's Services (RGE110927) and the London Boroughs Research Governance Framework (CERGF113). Fieldworkers have had advanced Criminal Records Bureau clearance. Findings will be disseminated through peer-reviewed publications, national and international conferences, through participating schools and the study website () %U https://bmjopen.bmj.com/content/2/4/e001840