%0 Journal Article %T Vitamin D and Its Association with Glycemic Status in Bangladeshi Adults with Newly Detected Type 2 Diabetes Mellitus %A Md. Firoj Hossain %A Tahniyah Haq %A Md. Fariduddin %A Shahjada Selim %A M. A. Hasanat %A Md. Shahed-Morshed %J Open Journal of Endocrine and Metabolic Diseases %P 1-11 %@ 2165-7432 %D 2021 %I Scientific Research Publishing %R 10.4236/ojemd.2021.111001 %X
Background: Very limited data are available regarding the association of vitamin D with glycemic status among adults with newly detected type 2 diabetes mellitus (T2DM) in Bangladesh. Objectives: To determine vitamin D status and its association with glycemic status in Bangladeshi adults with newly detected T2DM. Materials and Methods: This cross-sectional study was carried out in 102 newly detected T2DM diagnosed on the basis of the American Diabetes Association 2017 criteria (age: 42.95 ¡À 10.68 yrs.; m/f: 44/58) and equal number of age and sex matched controls (age: 40.43 ¡À 11.04 years) recruited consecutively from the Department of Endocrinology, BSMMU to measure serum vitamin D by high performance liquid chromatography method. Results: Both vitamin D deficiency (<20 ng/ml) (87.3% vs. 74.5%, p < 0.03) and severe vitamin D deficiency (<10 ng/ml) (56.2% vs. 26.3%, p < 0.001) were significantly higher in people with T2DM than control population. The mean level of 25(OH)D was significantly lower in adults with T2DM than control population (12.41 ¡À 6.85 ng/ml vs. 15.74 ¡À 6.25 ng/ml, p < 0.001). A significant inverse correlation was observed between vitamin D & HbA1c (r = &#45;0.249, p = 0.011) in patients with T2DM. HbA1c was linearly associated with vitamin D (¦Â = &#45;0.26, p = 0.009) and severe vitamin D deficiency by binary (OR = 1.37, p = 0.003) and multinomial logistic regression (HbA1c ¡Ý 10%: OR = 4.25, p = 0.04) in people with T2DM after adjustment for age and BMI. Conclusions: Severe vitamin D deficiency was positively associated with T2DM and inversely associated with HbA1c in patients with newly detected T2DM.
%K Vitamin D %K Type 2 Diabetes Mellitus %K Vitamin D Deficiency %K Glycated Hemoglobin A< %K sub> %K 1< %K /sub> %K c %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=106570