%0 Journal Article
%T Effect of Botulinum Toxin-A Injection on Intraocular Pressure and Proptosis in Thyroid Associated Orbitopathy
%A Boji£¿
%A Lovro
%A Galetovi£¿
%A Davor
%A Ivani£¿evi£¿
%A Milan
%A Le£¿in
%A Mladen
%A Le£¿tin
%A Jo£¿ko
%A Rogo£¿i£¿
%A Veljko
%A Romac
%A Rinaldo
%J -
%D 2009
%X Sa£¿etak The aim of this study was to evaluate the effects of extraocular muscle injection of botulinum toxin-A (BTX-A) on intraocular pressure (IOP) and proptosis in patients with ocular motility disturbances in thyroid associated orbitopathy (TAO). In 17 patients (20 eyes) with restrictive strabismus and diplopia, BTX -A injections were applied. Intraocular pressure was measured with a Goldmann applanation tonometer in primary gaze position before and 2¨C4 weeks after BTX-A injection. Extraorbital prominention of the eyeball was measured before and after BTX -A injection using a Hertel instrument. Before the injection, the mean IOP in primary position of gaze was 18.6¡À 2.8 mmHg and 2¨C4 weeks after BTX-A injection was 16.9¡À3.3 mmH; (p=0.001). There was no statistically significant difference in Hertel egzophthalmometer readings before and after BTX-A injection, 21.5¡À2.7 mm vs 22.0¡À 2.6 mm; (p=0.678). In conclusion, BTX-A injection has a secondary lowering effect on IOP in TAO due to relaxation of extraocular muscles, but with no influence on proptosis
%K thyroid related orbitopathy
%K botulinum toxin-A
%K intraocular pressure
%K proptosis
%U https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=78806