%0 Journal Article
%T Mixed Oxides as Successful Sorption Materials for Some Active Pharmaceutical Ingredients
%A Sekerov¨¢
%A L.
%A Semr¨¢dov¨¢
%A A.
%A Vrbkov¨¢
%A E.
%A Vysko£¿ilov¨¢
%A E.
%A £¿erveny
%A L.
%J -
%D 2020
%R 10.15255/CABEQ.2020.1774
%X Sa£¿etak Mixed oxides based on Mg-Al, Mg-Fe, Zn-Al, and Ni-Mg-Al were prepared, characterized and used as sorption materials for different types of active pharmaceutical ingredients (APIs)¨C nicotinic acid, salicylic acid, ibuprofen, paracetamol and ascorbic acid. Immobilization of APIs on solid supports was confirmed using X-Ray diffraction and infrared spectroscopy. Overall, the best sorption material for mentioned substances showed to be mixed Mg-Al oxides (>80 % of immobilized substance after 4 h except ascorbic acid). On the other hand, Mg-Fe and Mg-Ni-Al materials did not possess high sorption capacity (max. 59 % after 4 h). From studied substances, the immobilization amount was the lowest in the case of ascorbic acid (max. 44 % immobilized after 4 h), the highest amount was immobilized in the case of salicylic and nicotinic acids (>95 %, 4 h). The discussion regarding the structure of substances and properties of sorption materials is also offered. This work is licensed under a Creative Commons Attribution 4.0 International License
%K API immobilization
%K sorption
%K mixed oxides
%U https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=344199