%0 Journal Article %T The Role of Cigarette Smoking and Alcohol Consumption in Pulmonary Tuberculosis Development and Recurrence %A Bari£¿i£¿ %A Bla£¿enka %A Bingulac-Popovi£¿ %A Jasna %A Juki£¿ %A Irena %A Lampalo %A Marina %A Popovi£¿-Grle %A Sanja %A Safi£¿ Stani£¿ %A Hana %J - %D 2019 %R 10.20471/acc.2019.58.04.04 %X Sa£¿etak During a two-year period (2001-2003), 464 patients were treated for tuberculosis at Jordanovac Department for Lung Diseases in Croatia. Besides pulmonary tuberculosis in 97.7% of patients, patients were also treated for tuberculous pleurisy (0.9%), tuberculous laryngitis (0.6%), tuberculous meningitis (0.2%), tuberculous pericarditis (0.2%) and urogenital tuberculosis (0.4%). Out of the total number of patients, 57.3% declared themselves to be active smokers (men were predominant and made up to 80.8%) and 20.9% to be active alcohol consumers. Both risk factors, i.e. smoking and alcohol consumption, were present in 15.1% of all patients. The most common comorbidities were diabetes mellitus (30.4%), cardiac diseases (11.2%) and chronic obstructive pulmonary disease (8.0%). Lung carcinoma was the most common malignant disease (n=51), with Mycobacterium tuberculosis isolated in 33% of them. Seventy-two of 464 (15.5%) patients had recurrences of tuberculosis. Of these, 30.5% had one of the risk factors (20.8% were smokers and 9.7% consumed alcohol), while 32.5% of patients had both risk factors. In conclusion, cigarette smoking was proved to be the most significant risk factor for development of pulmonary tuberculosis and its recurrence %K Tuberculosis %K Cigarette smoking %K Alcoholism %K Mycobacterium tuberculosis %K Croatia %U https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=341662