%0 Journal Article
%T ¡°Green¡± Synthesis of Sucrose Octaacetate and Characterization of Its Physicochemical Properties and Antimicrobial Activity
%A Denev
%A P.
%A Grudeva
%A R.
%A Koleva
%A M.
%A Petkova
%A N.
%A Tumbarski
%A Y.
%A Vasileva
%A I.
%A Vassilev
%A D.
%J -
%D 2017
%R 10.15255/CABEQ.2017.1117
%X Sa£¿etak Sucrose octaacetate (octa-O-acetylsucrose) has been synthesized by esterification of sucrose with acetic anhydride using ultrasound-assisted irradiation. This sucrose ester is a white, water-insoluble substance with a bitter taste. The FT-IR and NMR spectra confirmed acetylation and revealed the hydrophobic incorporation in sucrose molecule. Furthermore, the foamability, foam stability, emulsification and antimicrobial properties of octa-O-acetylsucrose were evaluated. Foams and 50 % (oil/water) model emulsions were prepared with 2 % (w/w) octa-O-acetylsucrose. The obtained results demonstrate the formation of emulsions and foams with high stability (50¨C70 %). The antimicrobial activity of octa-O-acetylsucrose was evaluated against seventeen microorganisms (Gram-positive and Gram-negative bacteria, yeasts, and fungi). Octa-O-acetylsucrose inhibited the growth of fungi Penicillium sp., Rhizopus sp. and Fusarium moniliforme at 5 mg cm¨C3, and yeasts Candida albicans at 1 mg cm¨C3. Inhibition against Gram-positive and Gram-negative bacteria was not observed. The obtained results demonstrate the potential applications of octa-O-acetylsucrose as a foaming agent, oil-in-water emulsion stabilizer, and antifungal substance in pharmaceutical and cosmetic preparations. This work is licensed under a Creative Commons Attribution 4.0 International License
%K octa-O-acetylsucrose
%K ultrasound-assisted synthesis
%K foam
%K antimicrobial properties
%U https://hrcak.srce.hr/index.php?show=clanak&id_clanak_jezik=283610