%0 Journal Article
%T Intravitreal Injections in Arc Sterile Setting: Safety Profile after More Than 10,000 Treatments
%A Alessio
%A Giovanni
%A Bini
%A Vito
%A Boscia
%A Francesco
%A Furino
%A Claudio
%A Grassi
%A Maria Oliva
%A Nacucchi
%A Annalisa
%A Recchimurzo
%A Nicola
%A Reibaldi
%A Michele
%J -
%D 2020
%R https://doi.org/10.1155/2020/3680406
%X Purpose. To report the occurrence of endophthalmitis and other complications after intravitreal injections (IVIs) in the Arc Sterile setting. Methods. A retrospective study that enrolled all patients who underwent IVIs between November 2017 and March 2019, collecting data about the patient¡¯s gender and age, type of injected drug, diagnosis, other ocular pathologies, physician and possible occurrence of endophthalmitis, or other complications. Results. Ten thousand and eighty-three IVIs were performed during the study period, involving 2014 eyes of 1,670 patients with an average age of 71.37£¿¡À£¿11.63 years. The injected drugs included ranibizumab (54.6%), aflibercept (38.0%), dexamethasone (6.7%), pegaptanib (0.3%), bevacizumab (0.4%), and ocriplasmin (0.01%). The diagnosis included neovascular age-related macular degeneration (859), myopic choroidal neovascularization (154), diabetic macular edema (576), retinal vein occlusion (203), and miscellaneus diagnosis (222). No cases of endophthalmitis were recorded. One hundred and sixty-nine cases of ocular hypertension were detected, while the most frequent complication was subconjunctival hemorrhage, identified after 1,180 IVIs. The residents performed over 80% of IVIs, but there was no statistically significant difference in incidence of complications between the residents group and consultants group. Conclusions. Arc Sterile seems to be a safe setting in which IVIs can be carried out, regarding infective risk, and it is easy to set up compared to operation theatre and useful to improve intravitreal injections governance
%U https://www.hindawi.com/journals/joph/2020/3680406/