%0 Journal Article %T Effect of JumpstartMD, a Commercial Low-Calorie Low-Carbohydrate Physician-Supervised Weight Loss Program, on 22,407 Adults %A Bourke %A Sean %A Morton %A John Maga£¿a %A Williams %A Paul %J - %D 2020 %R https://doi.org/10.1155/2020/8026016 %X Background. Commercial weight loss programs provide valuable consumer options for those desiring support. Several commercial programs are reported to produce ¡Ý3-fold greater weight loss than self-directed dieting. The effectiveness of JumpstartMD, a commercial pay-as-you-go program that emphasizes a low-to-very-low-carbohydrate real-food diet and optional pharmacologic treatment without prepackaged meals or meal replacement, has not previously been described. Methods. Completer and last observation carried forward (LOCF) of clinic-measured weight loss (kg) in 18,769 female and 3638 male JumpstartMD participants. Results. Completers lost (mean£¿¡À£¿SE) 8.7£¿¡À£¿0.04£¿kg, 9.5£¿¡À£¿0.04% with 44.5£¿¡À£¿0.5% achieving ¡Ý10% weight loss at 3 months (mo, N£¿=£¿14,999 completers); 11.8£¿¡À£¿0.1£¿kg, 12.6£¿¡À£¿0.1% with 66.4£¿¡À£¿0.6% achieving ¡Ý10% weight loss at 6£¿mo (N£¿=£¿11,805); and 11.5£¿¡À£¿0.2£¿kg, 12.0£¿¡À£¿0.2% with 57.6£¿¡À£¿0.9% achieving ¡Ý10% weight loss at 12£¿mo (N£¿=£¿8514). LOCF estimates were £¿6.5£¿¡À£¿0.03£¿kg, £¿7.2£¿¡À£¿0.03% with 27.1£¿¡À£¿0.3% achieving ¡Ý10% weight loss at 3£¿mo; £¿7.7£¿¡À£¿0.04£¿kg, £¿8.5£¿¡À£¿0.04% with 36.3£¿¡À£¿0.3% achieving ¡Ý10% weight loss at 6£¿mo; and £¿7.7£¿¡À£¿0.1£¿kg, £¿8.4£¿¡À£¿0.1% with 34.6£¿¡À£¿0.3% achieving ¡Ý10% weight loss after 12£¿mo. Frequent health coach meetings was a major determinant of weight loss, with women and men attending ¡Ý75% of their weekly appointments losing 8.8£¿¡À£¿0.04 and 11.9£¿¡À£¿0.1£¿kg, respectively, after 3£¿mo, 13.1£¿¡À£¿0.1 and 16.5£¿¡À£¿0.3£¿kg after 6£¿mo, and 16.5£¿¡À£¿0.3 and 19.4£¿¡À£¿0.8£¿kg after 12£¿mo. Phentermine and phendimetrazine had a minor effect in women only at 1 (6.1% greater weight loss than untreated), 2 (4.1%), and 3£¿mo (1.2%), but treated patients showed longer enrollment than nontreated during the first 3 (females: +0.4£¿¡À£¿0.01; males: +0.3£¿¡À£¿0.04£¿mo), 6 (females: +1.1£¿¡À£¿0.04; males: +1.0£¿¡À£¿0.1£¿mo), and 12£¿mo (females: +2.7£¿¡À£¿0.1; males: +2.4£¿¡À£¿0.2£¿mo). JumpstartMD produced generally greater weight loss than published reports for other real-food and prepackaged-meal commercial programs and somewhat greater or comparable losses to meal replacement diets. Conclusion. A one-on-one medically supervised program that emphasized real low-carbohydrate foods produced effective weight loss, particularly in those attending ¡Ý75% of their weekly appointments %U https://www.hindawi.com/journals/jobe/2020/8026016/