%0 Journal Article %T Atypical Manifestation of DRESS Syndrome %A Hakim %A Christopher %A Melitas %A Constantine %A Ngo %A Kha %A Nguyen %A Eric %J - %D 2020 %R https://doi.org/10.1155/2020/6863582 %X The differential for liver transaminases over 1000£¿units/liter typically includes liver ischemia, acute viral hepatitis, acetaminophen toxicity, and autoimmune hepatitis. Prompt evaluation is imperative as these etiologies can lead to fulminant liver failure. We present a case of transaminases over 1000£¿units/liter from an atypical etiology. A 52-year-old male, previously treated with allopurinol for an acute gout flare, presented with persistent fevers. Given that he had taken a ¡°high-risk medication¡± 2¨C6 weeks before presentation, subsequently presented with fever, rash, renal impairment, elevated liver enzymes in the thousands, and peripheral eosinophilia, DRESS syndrome secondary to allopurinol was diagnosed %U https://www.hindawi.com/journals/crigm/2020/6863582/