%0 Journal Article
%T Stevens¨CJohnson Syndrome and Herpes Simplex Type 1 Infection during Adalimumab Therapy for CrohnˇŻs Disease
%A Apolito
%A Pasquale
%A Biagini
%A Maria Rosa
%A Galli
%A Andrea
%A Innocenti
%A Tommaso
%A Lynch
%A Erica Nicola
%A Macr¨¬
%A Giuseppe
%A Mello
%A Tommaso
%A Milani
%A Stefano
%A Milla
%A Monica
%A Parisio
%A Laura
%A Roselli
%A Jenny
%A Tarocchi
%A Mirko
%J -
%D 2020
%R https://doi.org/10.1155/2020/3875024
%X Stevens¨CJohnson syndrome (SJS) is a severe mucocutaneous adverse drug reaction with a relatively high mortality rate. SJS is described during herpes simplex virus type 1 (HSV1) infection and, rarely, even during adalimumab therapy. We report the case of a patient with CrohnˇŻs disease who developed SJS during an HSV1 infection and a contemporaneous anti-TNF¦Á therapy with adalimumab. Remission was achieved with suspension of adalimumab and high doses of intravenous steroids and antivirals. Patients with HSV1 infection and on adalimumab therapy have a combined risk of SJS and should be monitored closely
%U https://www.hindawi.com/journals/crigm/2020/3875024/