%0 Journal Article
%T Prolonged Hypercalcemia-Induced Psychosis
%A Aziz
%A Rehan
%A Mangini
%A Pratheek
%A Nagy
%A Lauren
%A Schroen
%A Caitlin
%A Tobia
%A Anthony
%J -
%D 2020
%R https://doi.org/10.1155/2020/6954036
%X Hypercalcemia is known to cause neuropsychiatric dysfunction including mood and cognitive changes and rarely, acute psychosis. High calcium levels can be a catalyst for neuronal demise, possibly due to glutaminergic excitotoxicity and dopaminergic and serotonergic dysfunction. While restoration of normal calcium levels or removal of a parathyroid adenoma has been shown to rapidly resolve neuropsychiatric symptoms, there have been rare reported cases of primary hyperparathyroid-related hypercalcemia with persistent symptoms of psychosis. In this case report, we will describe a patient with no past psychiatric history presenting with a protracted course of delirium and psychosis after a removal of a parathyroid adenoma which had caused prolonged exposure to hypercalcemia. The patient¡¯s psychosis was unresponsive to psychotropic medication and required inpatient psychiatric care after medical clearance. Per medical records, before the patient was ultimately lost to follow-up, she continued to suffer from psychotic symptoms for at least 8 months. We will discuss the patient¡¯s unusual hospital course and management and offer suggestions for future study
%U https://www.hindawi.com/journals/crips/2020/6954036/