%0 Journal Article
%T Gold(I) Complexes with Ferrocenylphosphino Sulfonate Ligands: Synthesis and Application in the Catalytic Addition of Carboxylic Acids to Internal Alkynes in Water
%J Catalysts | An Open Access Journal from MDPI
%D 2019
%R https://doi.org/10.3390/catal9110955
%X The synthesis and characterization of novel gold(I) complexes containing hydrophilic ferrocenylphosphino sulfonate ligands, i.e., compounds [AuCl{( ¦Ç 5-C 5H 3PR 2(SO 3 iPr))Fe( ¦Ç 5-C 5H 5)}] (R = Ph ( 2a), p-Tol ( 2b), Cy ( 2c)), are presented, including a single-crystal X-ray diffraction study on 2a. Complexes 2a¨C c were checked as catalysts for the intermolecular addition of carboxylic acids to nonactivated internal alkynes using water as a green reaction medium. The best results in terms of activity were obtained with 2a in combination with AgOAc, which was able to promote the selective anti addition of a variety of aromatic, aliphatic, and ¦Á,¦Â-unsaturated carboxylic acids to both symmetrical and unsymmetrical internal alkynes at 60 ¡ãC, employing metal loadings of only 2 mol %. View Full-Tex
%U https://www.mdpi.com/2073-4344/9/11/955