%0 Journal Article
%T Uterine Tumors Resembling Ovarian Sex Cord Tumors in Four Baboons (Papio spp.)
%A Edward J. Dick
%A Ekaterina Perminov
%A Emily M. Corbin
%A Erica K. Barkei
%A Olga Gonzalez
%A Sara Mangosing
%A Shyamesh Kumar
%J Veterinary Pathology
%@ 1544-2217
%D 2018
%R 10.1177/0300985818766208
%X Uterine tumors resembling ovarian sex cord tumors (UTROSCTs) are rare uterine neoplasms that exhibit prominent sex cord-like differentiation. The authors describe 4 cases of UTROSCTs that were identified as incidental lesions in female baboons. All baboons were in good body condition. One animal had a 2-mm-diameter yellow-tan mass in the uterine body along the attachment of the left broad ligament; the other 3 did not have any gross lesions in the uterus. Histologically, the myometrium contained multifocal well-demarcated neoplasms composed of cuboidal to columnar cells arranged in variable arrangements of sheets, nests, cords, trabecular, and retiform patterns that occasionally formed Call-Exner-like bodies. In all cases, the neoplastic cells were diffusely positive for WT-1 and negative for calretinin, CD99, and desmin. One case was positive for inhibin and CD10. To the best of the authors¡¯ knowledge, this is the first report of UTROSCTs in nonhuman primates and in the veterinary literature
%K sex cord-gonadal stromal tumors
%K endometrial stromal tumors
%K uterus
%K neoplasia
%K ovarian neoplasms
%K primates
%U https://journals.sagepub.com/doi/full/10.1177/0300985818766208