%0 Journal Article
%T Inside the Bronchus
%A Carina R£¿lo Silvestre
%A Andr¨¦ Nunes
%A Ricardo Cordeiro
%A Daniel Duarte
%A Jo£¿o Eus¨¦bio
%A Teresa Falc£¿o
%A Ant¨®nio Domingos
%J Open Journal of Internal Medicine
%P 239-243
%@ 2162-5980
%D 2020
%I Scientific Research Publishing
%R 10.4236/ojim.2020.102025
%X Tumor necrosis factor inhibitors contribute to a greater susceptibility to infection or reactivation of Mycobacterium tuberculosis. Endobronchial tuberculosis has non-specific symptoms, which may delay the diagnosis. We report a case of a 21-year-old woman, with Crohn¡¯s disease, medicated with adalimumab. The patient presented with a 2-week history of fever, dry cough, pleuritic chest pain and weight loss of 2 kg. Chest imaging showed bilateral nodular opacities, at the right pulmonary apex. Bronchoscopy revealed a tumorous lesion in the right upper bronchus. Bronchial biopsies were suggestive of chronic granulomatous inflammation. Bronchoalveolar lavage produced a positive for acid-fast bacilli smear and culture for Mycobacterium tuberculosis. We assumed the diagnosis of tuberculosis with endobronchial manifestations. Nowadays this is a rare manifestation. Empirical treatment for tuberculosis was initiated, with steroids as an adjunct therapy to prevent bronchostenosis, with clinical and radiological improvement.
%K Tuberculosis
%K Crohn¡¯s Disease
%K TNF-<
%K i>
%K ¦Á<
%K /i>
%K Inhibitors
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=100832